DILANTIN® (extended phenytoin sodium capsules) Site Map | Safety Info

DILANTIN is available in 30-mg and 100-mg capsules.


Do not take DILANTIN if you:

  • Are allergic to phenytoin or its inactive ingredients or other anticonvulsants such as CEREBYX (fosphenytoin), PEGANONE (ethotoin), or MESANTOIN (mephenytoin)
  • Have had liver problems from taking phenytoin
  • Take delavirdine (a drug which may be prescribed to you when you suffer from an HIV infection) since DILANTIN modifies its effect

Do not stop taking DILANTIN without first talking to your healthcare provider. Stopping DILANTIN suddenly can cause serious problems. Stopping a seizure medicine suddenly in a patient who has epilepsy can cause seizures that will not stop (status epilepticus).

Do not change your dose of DILANTIN without talking to your healthcare provider. Only your doctor can recommend changing your medication. When a change in the dosage form or brand is prescribed, careful monitoring of phenytoin serum levels should be carried out by your doctor.

Like other antiepileptic drugs, DILANTIN may cause suicidal thoughts or actions in a very small number of people, about 1 in 500. Before you take DILANTIN, tell your healthcare provider if you have or have had depression, mood problems, or suicidal thoughts or behavior. Call a healthcare provider right away if you have thoughts about suicide or dying, attempts to commit suicide, new or worse depression, new or worse anxiety, feeling agitated or restless, panic attacks, trouble sleeping (insomnia), new or worse irritability, acting aggressive, being angry, or violent, acting on dangerous impulses, an extreme increase in activity and talking (mania), other unusual changes in behavior or mood.

DILANTIN can cause a type of serious allergic reaction that may affect different parts of the body such as your liver, kidneys, blood, heart, skin or other parts of your body. These can be very serious and cause death. Call your healthcare provider right away if you have any or all of these symptoms:

  • Fever
  • Sore throat
  • Not wanting to eat (anorexia)
  • Rash
  • Sores in your mouth
  • Nausea
  • Swollen lymph glands
  • Swelling of your face,
    eye, lips, or tongue
  • Trouble swallowing or
  • Bruise easily
  • Purple or red spots on
    your skin
  • Increased infections
  • Vomiting
  • Yellowing of the skin and the
    white parts of your eyes (jaundice)

If you experience a rash while taking DILANTIN, or any of the symptoms listed below, contact your doctor immediately. DILANTIN may cause serious side effects including:

  • A serious, life-threatening disorder called Stevens-Johnson syndrome and Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) which can be fatal
  • Softening of your bones (osteopenia, osteoporosis, and osteomalacia). This can cause broken bones
  • High levels of DILANTIN in your blood that could cause confusion also known as delirium, psychosis or a more serious condition that affects how your brain works (encephalopathy)
  • DILANTIN can cause overgrowth of your gums. Brushing and flossing your teeth and seeing a dentist regularly while taking DILANTIN can help prevent this

Before you take DILANTIN, inform your doctor or pharmacist of all the medications you take including prescription and over-the-counter medicines and any medical conditions you have including if you:

  • Have kidney or liver problems as you may show early signs of toxicity. DILANTIN may cause liver damage
  • Have or had porphyria (por-FER-ee-ah). DILANTIN has been associated with harmful effects on blood cells
  • Have or had diabetes. Your blood sugar level can be altered while taking DILANTIN

If you take DILANTIN during pregnancy, your baby is at risk for serious birth defects and bleeding problems right after birth. Your healthcare provider may give you and your baby medicine to prevent this. All women of child-bearing age should talk to their healthcare provider about using other possible treatments instead of DILANTIN. Tell your doctor if you are breastfeeding or plan to breastfeed. DILANTIN can pass into breast milk.

Taking DILANTIN with certain other medicines can cause side effects or affect how well they work. Do not start or stop other medicines without talking to your healthcare provider.

Do not drink alcohol while you take DILANTIN without first talking to your healthcare provider. Drinking alcohol while taking DILANTIN may change your blood levels of DILANTIN which can cause serious problems.

The most common side effects of DILANTIN include irregular movement of the eye, problems with walking and coordination, slurred speech, trouble sleeping, confusion, dizziness nervousness, tremor, headache, and nausea.

All brands are trademarks of their owners.


DILANTIN is a prescription medicine used to treat certain types of seizures called tonic-clonic (grand mal), psychomotor (temporal lobe) seizures, and to prevent and treat seizures that happen during or after brain surgery.

Please see Full Prescribing Information and Medication Guide.

Patients should always ask their doctors for medical advice about adverse events.
You may report an adverse event related to Pfizer products by calling 1-800-438-1985 (US only). If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. The FDA has established a reporting service known as MedWatch where health care professionals and consumers can report serious problems they suspect may be associated with the drugs and medical devices they prescribe, dispense, or use. Visit MedWatch or call 1-800-FDA-1088.

Terms and Conditions

By using the DILANTIN Savings Card, you acknowledge that you currently meet the eligibility criteria and will comply with the following terms and conditions.

  • The Card is not valid for prescriptions that are eligible to be reimbursed, in whole or in part, by Medicaid, Medicare, or other federal or state healthcare programs (including any state prescription drug assistance programs and the Government Health Insurance Plan available in Puerto Rico [formerly known as "La Reforma De Salud"])
  • The Card is not valid for prescriptions that are eligible to be reimbursed by private insurance plans or other health or pharmacy benefit programs that reimburse you for the entire cost of your prescription drugs
  • You must be 18 years or older
  • By using the Card, you will receive savings of up to $20 off per fill, for a maximum savings of $240 per card 
  • You must deduct the value received under this program from any reimbursement request submitted to your insurance plan, either directly by you or on your behalf
  • The Card is not valid for Massachusetts residents whose prescriptions are covered in whole or in part by third-party insurance, or where otherwise prohibited by law
  • The Card cannot be combined with any other rebate or coupon, free trial, or similar offer for the specified prescription
  • The Card will be accepted only at participating pharmacies
  • The Card is not health insurance
  • This offer is good only in the United States and Puerto Rico
  • The Card is limited to one per person during this offering period and is not transferable
  • Pfizer reserves the right to rescind, revoke, or amend the Card without notice
  • Offer expires 12/31/18